Found 471 matching trials
Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11) PHASE2 The purpose of this study is to evaluate the safety and efficacy of pembrol...
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St Joseph Heritage Healthcare-Oncology ( Site 0004)
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Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007) PHASE3 The primary objective of the study is to compare sacituzumab tirumotecan co...
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Mayo Clinic in Arizona - Phoenix ( Site 0147)
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Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours PHASE1 The Phase I trial is evaluating safety, tolerability, pharmacokinetics and ...
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Herlev and Gentofte Hospital, Center for Cancer Research
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AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors PHASE1 The purpose of this first-in-human study is to evaluate the safety, tolerab...
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City of Hope National Medical Center
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A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer PHASE1 The purpose of this study is to determine safety and preliminary efficacy o...
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University of California at San Diego Moores Cancer Center
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Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies PHASE1 This study is a Phase I/II, multicenter, first-in-human, open-label dose-es...
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Active Not Recruiting
Location
Sarah Cannon Research Institute at HealthONE
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Circulating Tumor DNA Alterations in Non-small Cell Lung Cancer Patients Treated With Pembrolizumab N/A The purpose of this study is to learn how to use blood tests to better pred...
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Columbia University Irving Medical Center
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Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors PHASE1 This is a First-in-Human, Phase 1, Dose-Escalation and Dose-Expansion study...
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Massachusetts General Hospital
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Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung Cancer PHASE2 The goal of this clinical trial is to compare the safety and efficacy (how ...
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Active Not Recruiting
Location
St. Joseph Heritage Healthcare
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TAC T-cells for the Treatment of HER2-positive Solid Tumors PHASE1 TAC01-HER2 is a novel cell therapy that consists of genetically engineered ...
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Lurie Cancer Center - Northwestern University
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